【佳学基因检测】cDNA微阵列：基因特征的鉴定及其在临床实践中的应用

靶向药一旦停药会怎样省钱要点

查重分析《肿瘤治疗效果与基因检测结果的相关性》《J BUON》在 2007 Sep;12 Suppl 1:S39-44发表了一篇题目为《cDNA微阵列：基因特征的鉴定及其在临床实践中的应用》肿瘤靶向药物治疗基因检测临床研究文章。该研究由Zvonko Magic, Sinisa Radulovic, Mirjana Brankovic-Magic等完成。促进了肿瘤的精准治疗与个性化用药的发展，进一步强调了基因信息检测与分析的重要性。

肿瘤靶向药物及精准治疗临床研究内容关键词：

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肿瘤靶向治疗基因检测临床应用结果

人类基因组测序为医学带来了新的后基因组时代。一种新的微阵列技术代表了一种新的遗传平台，它被广泛用于弥合基因序列和功能之间的差距。基本上，使用这种技术，可以同时测量基因组中几乎所有基因的活性。这些实验的结果是斑点的亮度因基因而异，对应于所检查基因的转录活性。它可以创建实验来寻找其表达与肿瘤的存在、从良性疾病进展到恶性疾病或从低级别到高级别恶性肿瘤的进展相关的基因。可以更具体地识别肿瘤类型，并且可以使用基因表达的差异来检测已经证明与转移风险增加相关的基因表达变化的肿瘤。基因表达谱还将帮助临床医生就癌症患者的最佳治疗做出决定。

肿瘤发生与复发转移国际数据库描述：

Sequencing of human genome introduced the new postgenomic era in medicine. A novel microarray technology represents a novel genetic platform which is being widely exploited to bridge the gap between gene sequence and function. Basically, with this technique it is possible to simultaneously measure the activity of virtually all genes in the genome. The result of these experiments are spots whose brightness varies from gene to gene corresponding to the transcriptional activity of the examined genes. It makes it possible to create experiments looking for genes whose expression correlates with the presence of tumor, with progression from a benign to a malignant condition, or with progression from a low grade to high grade malignancy. Tumor types can be more specifically identified, and differences in gene expression can be used to detect tumors that already demonstrate gene expression changes associated with increased risk of metastasis. Gene expression profiles will also help clinicians make decisions about the optimal treatment of cancer patients.