【佳学基因检测】基因调控网络：分析乳腺癌发生、发展与药物反应的新概念框架

全国十大基因检测公司排名简介

研讨《肿瘤致病基因突变位点的性质及影响分析》时，发现《Ann Oncol》在 2011 Jun;22(6):1259-1265发表了一篇题目为《基因调控网络：分析乳腺癌行为的新概念框架》肿瘤靶向药物治疗基因检测临床研究文章。该研究由R Demicheli, D Coradini 等完成。促进了基因突变解码及基因背景对乳腺癌发生发展的影响，进一步强调了基因信息检测与分析的重要性。

肿瘤靶向药物及精准治疗临床研究内容关键词：

基因调控,网络,乳腺癌,行为,新概念,框架

肿瘤靶向治疗基因检测临床应用结果

对复杂系统的研究清楚地证明，一些整体行为属性不能从它们单个部分的属性中推断出来，而是由它们的架构决定的。最近在生物学中提出了这种方法以了解基因组功能，并在肿瘤学中提出了对各种癌症行为的更一致的解释。从目前的角度来看，我们总结了所提出的全局方法的基本概念，然后在这个新的背景下重新考虑肿瘤休眠和原发性肿瘤切除效应，这最近成为理解乳腺癌的关键点。

肿瘤发生与复发转移国际数据库描述：

The study of complex systems has clearly evidenced that a few overall behavioural properties cannot be inferred from the properties of their single parts and are rather determined by their architecture. Such an approach has been recently proposed in biology to understand genome functioning and in oncology to endeavour a more consistent explanation of the variegated cancer behaviours. In the present perspective, we summarise the basic concepts of the proposed global approach and then we reconsider, in this new context, tumour dormancy and primary tumour removal effects, which recently emerged as critical points for breast cancer understanding.